Skip to main content
Figure 4 | Cilia

Figure 4

From: Multiple essential roles for primary cilia in heart development

Figure 4

Atrioventricular septation is impaired in cbs mutants. Serial 10-μm transverse sections of E14.5 (A-C) and E16.5 (D-F) wild type and cbs/cbs embryos were stained with H & E. They are presented from cranial to caudal, and the left side of the body is to the right, dorsal is at the top of each panel. Dextrotransposition of the common trunk arising from the right ventricle (D,E) combined with both ASD (B,C,F) and VSD-pars membranacea (C,F) was recorded. The pericardium is also enlarged (C,F). An example of arteria lusoria (‘Al’) is indicated (D). Abbreviations (alphabetically arranged): Aa, ascending aorta; Al, arteria lusoria; Ao, aorta; Arc, aortic arch; At, thoracic aorta; CF, common foregut tube; Da, ductus arteriosus; E, esophagus; La, left atrium; Lp, left principal bronchus; Lpa, left pulmonary artery; Lv, left ventricle; Lvc, left superior vena cava; Pt, pulmonary trunk; PTA, persistent truncus arteriosus; Ra, right atrium; Rp, right principal bronchus; Rpa, right pulmonary artery; Rv, right ventricle; T, trachea; Tb, tracheal bifurcation; *, atrial septum defect (ASD); →, ventricular septum defect (VSD); arrowheads, outline of pericardium. Scale bar: 0.5 mm. cbs, cobblestone; E14.5, embryonic day 14.5.

Back to article page