Getting to the heart of intraflagellar transport using Trypanosoma and Chlamydomonas models: the strength is in their differences

Cilia

Table 1 Role of various IFT proteins and motors

Proteins have been grouped according to their category. When inhibition of a given gene blocked flagellum formation, it was described as an anterograde phenotype (A) and when it stopped retrograde transport, resulting in the formation of shorter flagella filled with IFT material, it was described as a retrograde phenotype (R). Ambiguous phenotypes are shown with a question mark and a hyphen indicates that the gene is conserved but has not been studied in that organism. A cross indicates that the gene is missing from the genome. Experiments were carried out by RNAi knockdown except where indicated. The asterisk denotes an insertion mutant whereas names of the mutant gene obtained by forward genetics are shown in italics

ISSN: 2046-2530