Figure 1
From: Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis
Structure of the primary cilium. The two centrioles are surrounded by the pericentrosomal matrix, serving as basal body and microtubule organizing center. Vesicular transport delivers ciliary components either to the basal body or ciliary pocket. Axonemal import is regulated by the transition zone, which is marked by Y-links. Anterograde kinesin-2- and retrograde dynein-2-mediated IFT sustain ciliary maintenance and cilia-dependent signaling; the complex rearranges at the ciliary tip.