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Table 1 Classification of EF-hand Proteins

From: Calcium sensors of ciliary outer arm dynein: functions and phylogenetic considerations for eukaryotic evolution

Family Subfamily Proteins
CTER (calmodulin, troponin C, essential and regulatory light chain) subfamily   calmodulin, troponin C, essential light chain of myosin, regulatory light chain of myosin
   Others: Ca2+/CaM protein kinase, calsenilin, DREAM, calcineurin B like (CBL) sensors
CRP (calcineurin B, p22, recoverin) subfamily   calcineurin B, p22, recoverin (and other neuronal calcium sensor family)
   Others: Ca2+/CaM protein kinase, calsenilin, DREAM, calcineurin B like (CBL) sensors
S100 subfamily   S100, calbindin D9k, P26olf (dicalcin)
   Fused gene family: profilaggrin, trichohyalin, repetin, hornerin, profilaggrin-related protein, cornulin
Other EF-hand subfamilies showing no strong congruence to one another PENTA-EF-hand subfamily Group II (calpain, calcium-dependent proteases, sorcin, grancalcin), Group I (ALG-2, peflin)
  Proteins with six EF-hands calbindin D28k, calretinin, Eps15 homology domain, CREC family (Ca2+-binding protein of 45 kDa, reticulocalbin, ER Ca2+-binding protein of 55 kDa, and calumenin), Plasmodium falciparum surface protein, calsymin
  Proteins with eight and 12 EF-hands Lytechinus pictus SPEC-resembling protein, EF12
  Proteins with four EF-hands Tetrahymena pyriformis calcium binding protein TCBP-25, TCBP-23, CBP, calcyphosine, Strongyrocentrotus purpuratus Ectoderm calcium binding protein SPEC, calflagin, sarcoplasm calcium binding protein, Hra32, EFH5, calcium vector protein, PM129 clone from Arabidopsis thaliana, calcium and integrin binding protein, spasmin, aequorin, Plasmodium falciparum protein kinase (PFCPK), protein phosphatase encoded by rdgC, phospholipase C, LAV1
  Proteins with two-EF-hands Phl p 7 (polcalcin), alpha-actinin, alpha-spectrin, calmodulin-related gene product encoded by T+, calsensin, groovin, diacylglycerol kinase, glycerol-3-phosphate dehydrogenase, fimbrin, ras guanyl nucleotide-releasing protein (GRP), polycystin-2, ryanodine receptor protein (RYR), CBL, nucleobindin, allograft inflammatory factor-1, BM-40 (osteonectin)
  EF-hand proteins in bacteria and viruses calerythrin, other EF-hand proteins in bacteria, MSV from pox virus
  1. The list is based on the chapter 11 of a book by Permyakov and Kretsinger (2011) [69].