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Fig. 2 | Cilia

Fig. 2

From: Comparing the Bbs10 complete knockout phenotype with a specific renal epithelial knockout one highlights the link between renal defects and systemic inactivation in mice

Fig. 2

Obesity-associated phenotype in Bbs10 −/− mice. a Growth curve of Bbs10 +/+ and Bbs10 −/− (n = 8). b Photograph of 3-month-old Bbs10 +/+ and Bbs10 −/− mice. c Food intake measurement of Bbs10 +/+ and Bbs10 −/− mice (n = 8 per genotype). d Measurement of the circulating concentrations of leptin in Bbs10 +/+ and Bbs10 −/− (n = 6 per group). e Pictures of AdipoRed-stained visceral adipocytes from Bbs10 +/+ and Bbs10 −/−. Scale bar 50 µm. Data are expressed as mean ± SEM. f Glucose tolerance test (GTT) and g insulin tolerance test (ITT) for the same mice (n = 7 per group). Values are expressed as mean ± SEM. *p < 0.05.

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Cilia

ISSN: 2046-2530

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