Fig. 1
From: Naegleria: a classic model for de novo basal body assembly
Naegleria differentiation. Amoebae can differentiate into flagellates, during which time they assemble basal bodies, flagella, flagellar rootlets, and a cortical microtubule cytoskeleton de novo. This process takes about an hour, and includes transcription and translation of basal body and flagella genes, including flagellar tubulin [5–9]. This process has been experimentally optimized to be highly synchronous and temporally reproducible [2, 3, 20, 25]