|
Centroid mass (m/z)
|
Glycan structure
|
UDP-3331 (% total glycans)
|
UDP-3331 +OFD1 (% total glycans)
|
UW172–4 (% total glycans)
|
Adult control (% total glycans)
|
Ref low (% total glycans)
|
Ref high (% total glycans)
|
|---|
|
1171.9
|
Hex3 HexNAc2
|
4.09
|
7.07
|
1.63
|
5.00
|
0.23
|
12.38
|
|
1346.0
|
Hex3 dHex1 HexNAc2
|
3.86
|
5.28
|
1.06
|
5.09
|
0.00
|
6.11
|
|
1417.1#
|
Hex3 HexNAc3
|
0.00
|
0.79
|
0.00
|
0.78
|
0.00
|
0.78
|
|
1580.2
|
Hex5 HexNAc2
|
8.19
|
11.68
|
4.55
|
8.46
|
1.83
|
14.29
|
|
1621.3
|
Hex4 HexNAc3
|
0.56
|
0.76
|
0.00
|
0.98
|
0.00
|
0.98
|
|
1662.3
|
Hex3 HexNAc4
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.29
|
|
1784.4
|
Hex6 HexNAc2
|
19.88
|
17.97
|
15.17
|
18.31
|
6.54
|
20.74
|
|
1825.4
|
Hex5 HexNAc3
|
0.57
|
0.62
|
0.00
|
0.90
|
0.00
|
0.90
|
|
1866.5
|
Hex4 HexNAc4
|
0.74
|
0.81
|
0.00
|
0.66
|
0.00
|
0.70
|
|
1982.5
|
Hex4 NeuAc1 HexNAc3
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.30
|
|
1988.5
|
Hex7 HexNAc2
|
9.81
|
9.62
|
12.04
|
9.67
|
4.87
|
14.86
|
|
2029.6
|
Hex6 HexNAc3
|
0.54
|
0.52
|
0.00
|
0.93
|
0.00
|
2.19
|
|
2070.6
|
Hex5 HexNAc4
|
4.39
|
4.03
|
2.03
|
3.20
|
0.00
|
3.88
|
|
2156.7#
|
Hex4 dHex1 HexNAc3 NeuAc1
|
0.00
|
0.34
|
0.00
|
0.52
|
0.00
|
0.75
|
|
2192.7
|
Hex8 HexNAc2
|
16.18
|
13.96
|
27.66
|
16.04
|
0.00
|
32.90
|
|
2227.7
|
Hex4 HexNAc4 NeuAc1
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.20
|
|
2396.9
|
Hex9 HexNAc2
|
9.28
|
7.49
|
18.11
|
9.09
|
0.24
|
32.34
|
|
2431.9^
|
Hex5 HexNAc4 NeuAc1
|
2.18
|
1.47
|
2.92
|
1.83
|
0.00
|
1.83
|
|
2606.0^
|
Hex5 dHex1 HexNAc4 NeuAc1
|
6.85
|
4.19
|
2.23
|
4.70
|
0.00
|
4.70
|
|
2793.3
|
Hex5 HexNAc4 NeuAc2
|
0.86
|
0.45
|
1.53
|
1.00
|
1.21
|
6.80
|
|
2967.3
|
Hex5 dHex1 HexNAc4 NeuAc2
|
2.69
|
1.45
|
4.74
|
2.02
|
3.38
|
10.79
|
|
3241.6
|
Hex6 HexNAc5 NeuAc2
|
0.00
|
0.00
|
0.00
|
0.17
|
0.00
|
1.96
|
|
3415.6
|
Hex6 dHex1 HexNAc5 NeuAc2
|
0.45
|
0.22
|
0.84
|
0.39
|
0.43
|
5.84
|
|
3602.9†
|
Hex6 HexNAc5 NeuAc3
|
0.33
|
0.00
|
0.00
|
0.28
|
0.64
|
23.23
|
|
3776.6#
|
Hex6 dHex1 HexNAc5 NeuAc3
|
0.21
|
0.00
|
0.79
|
0.11
|
0.00
|
5.46
|
- The percentages of total glycans of the indicated N-glycan species for UDP-3331, UDP-3331 + OFD1 rescue, UW172-4, and adult WT control fibroblasts samples are shown along with reference (Ref) low and high values derived from control samples. Species with values in the low-normal range in the JBTS10 sample(s) are flagged with a pound sign (#). Species that are elevated above the normal range in JBTS10 sample(s) are flagged with a caret (^). Species below the normal range in JBTS10 sample(s) are flagged with a dagger (†)
-
#Low normal in JBST10
-
^Above normal in JBST10
-
†Below normal in JBST10
