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Fig. 5 | Cilia

Fig. 5

From: Glioma cell proliferation is enhanced in the presence of tumor-derived cilia vesicles

Fig. 5

Ciliary vesicle formation occurs during the G0 phase of the GBM cell cycle. Arl13b:GFP+ clones were immunostained with antibodies against Ki67 (red), a marker of the active (non-G0) phases of the cell cycle, or aaTub (red), to identify cilia axonemes. Nuclei were stained with DAPI (blue). a, b Show lower magnification views of stained cells for the indicated antibodies. Boxes are enlarged in c. c Four examples (arranged in columns) of GBM primary cilia (arrowheads) that appear to have formed vesicles at their tip, on cells whose nuclei lack/display very weak levels of Ki67 (arrows). Scale bar in a, c = 10 μm

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