Figure 4From: Cilia, Wnt signaling, and the cytoskeletonDiagram of Cdc42 regulation of cytoskeletal rearrangement. Cdc42 can control polarity via two separate pathways. Activation of Par6/aPKC inhibits GSK-3, which results in polarization of microtubules (MT). Rac-dependent polarization of the actin cytoskeleton is due to Pak activated βPIX.Back to article page