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Figure 4 | Cilia

Figure 4

From: Cilia, Wnt signaling, and the cytoskeleton

Figure 4

Diagram of Cdc42 regulation of cytoskeletal rearrangement. Cdc42 can control polarity via two separate pathways. Activation of Par6/aPKC inhibits GSK-3, which results in polarization of microtubules (MT). Rac-dependent polarization of the actin cytoskeleton is due to Pak activated βPIX.

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