Enhanced response to pulmonary Streptococcus pneumoniae infection is associated with primary ciliary dyskinesia in mice lacking Pcdp1 and Spef2

Cilia

Table 1 Inflammatory cells in BAL fluid

Mouse line	Day post-infection	Total number of cells counted	Resident macrophages (%)	Infiltrating macrophages (%)	T lymphocytes (%)
Wild type	Uninfected	272	42	56	-
Wild type	2	441	79	12	6
Wild type	3	537	5	78	16
nm1054	Uninfected	184	99	-	-
nm1054	2	370	19	56	24
nm1054	3	513	-	53	42
bgh	Uninfected	261	99	-	-
bgh	2	632	56	12	26
bgh	3	463	-	17	82

Cell types were counted in pooled representative fields from three mice in each group in a blinded manner, and approximate percentages of the total number are shown. Percentages less than five are indicated by a dash, and only cell types representing at least 5% of the total cells are included.

ISSN: 2046-2530