Table 2 Summary of N-glycan profiles of JBTS10 patient plasma
Centroid mass (m/z) | Predicted glycan species | UDP-3331 (% total glycans) | NIH-452 (% total glycans) | Ref low (% total glycans) | Ref high (% total glycans) |
|---|---|---|---|---|---|
1580.2 | Hex5 HexNAc2 | 0.69 | 0.91 | 0.23 | 1.88 |
1662.3 | Hex3 HexNAc4 | 0.03 | 0.00 | 0.00 | 0.22 |
1784.4 | Hex6 HexNAc2 | 0.51 | 0.48 | 0.00 | 0.87 |
1866.5 | Hex4 HexNAc4 | 0.19 | 0.00 | 0.06 | 0.53 |
1982.5 | Hex4 NeuAc1 HexNAc3 | 0.48 | 0.43 | 0.08 | 0.80 |
1988.5 | Hex7 HexNAc2 | 0.19 | 0.00 | 0.00 | 0.39 |
2070.6 | Hex5 HexNAc4 | – | 0.15 | 0.00 | 0.30 |
2156.7# | Hex4 dHex1 HexNAc3 NeuAc1 | 0.05 | 0.00 | 0.06 | 0.17 |
2186.7 | Hex4 dHex1 NeuGc1 HexNAc3 | – | 0.39 | 0.00 | 0.89 |
2192.7 | Hex8 HexNAc2 | 0.32 | 0.00 | 0.06 | 0.61 |
2227.7^ | Hex4 HexNAc4 NeuAc1 | 1.38 | 1.54 | 0.40 | 1.28 |
2285.2^ | Hex4 dHex1 HexNAc5 | 0.17 | – | 0.00 | 0.16 |
2431.9^ | Hex5 HexNAc4 NeuAc1 | 5.87 | 9.88 | 2.38 | 6.74 |
2606.0 | Hex5 dHex1 HexNAc4 NeuAc1 | 0.54 | 1.87 | 0.79 | 2.87 |
2793.3† | Hex5 HexNAc4 NeuAc2 | 20.29 | 40.58 | 28.38 | 58.23 |
2966.5 | Hex5 dHex1 HexNAc4 NeuAc2 | 1.49 | 2.89 | 2.49 | 3.36 |
3241.6 | Hex6 HexNAc5 NeuAc2 | 1.13 | 1.52 | 0.08 | 1.70 |
3415.6 | Hex6 dHex1 HexNAc5 NeuAc2 | 0.25 | 0.00 | 0.00 | 0.87 |
3602.9 | Hex6 HexNAc5 NeuAc3 | 3.31 | 6.72 | 1.64 | 6.10 |
3776.6# | Hex6 dHex1 HexNAc5 NeuAc3 | 0.94 | 0.38 | 0.00 | 7.27 |