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Fig. 3 | Cilia

Fig. 3

From: Mutations in IFT-A satellite core component genes IFT43 and IFT121 produce short rib polydactyly syndrome with distinctive campomelia

Fig. 3

The IFT-A complex is altered in IFT43 mutants. a, b The absence of IFT43 in R06-303A amniocytes relative to control and reduction of IFT43 protein in R03-121A fibroblasts compared with control. a, c, d Levels of WDR19/IFT144, and motor protein DYNC2LI1 in control and mutant cells. GADPH served as a loading control. Bar graphs show statistical analyses (t test) for the replicates (n = 3) of each studied protein. e Cartoon of the core and satellite IFT-A complex proteins. Lines connecting the proteins represent known interactions

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Cilia

ISSN: 2046-2530

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