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  1. Content type: Research

    Primary cilia are microtubule-based organelles that protrude from the cell surface. Primary cilia play a critical role in development and disease through regulation of signaling pathways including the Hedgehog...

    Authors: Ina Menzl, Lauren Lebeau, Ritu Pandey, Nadia B Hassounah, Frank W Li, Ray Nagle, Karen Weihs and Kimberly M McDermott

    Citation: Cilia 2014 3:7

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  2. Content type: Research

    Assembly of primary cilia relies on vesicular trafficking towards the cilium base and intraflagellar transport (IFT) between the base and distal tip of the cilium. Recent studies have identified several key re...

    Authors: Kenneth B Schou, Stine K Morthorst, Søren T Christensen and Lotte B Pedersen

    Citation: Cilia 2014 3:6

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  3. Content type: Research

    Cilia and the sperm flagellum share many structural properties. Meiosis-specific nuclear structural 1 (MNS1) is a recently characterized protein that is abundantly expressed in post-meiotic spermatids and is r...

    Authors: Melissa L Vadnais, Angel M Lin and George L Gerton

    Citation: Cilia 2014 3:5

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  4. Content type: Research

    Bardet-Biedl syndrome (BBS) is an autosomal recessive ciliopathy disorder with 18 known causative genes (BBS1-18). The primary clinical features are renal abnormalities, rod-cone dystrophy, post-axial polydactyly...

    Authors: Mohamed H Al-Hamed, Charles van Lennep, Ann Marie Hynes, Paul Chrystal, Lorraine Eley, Fatimah Al-Fadhly, Riham El Sayed, Roslyn J Simms, Brian Meyer and John A Sayer

    Citation: Cilia 2014 3:3

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  5. Content type: Research

    Meckelin (MKS3), a conserved protein linked to Meckel Syndrome, assists in themigration of centrioles to the cell surface for ciliogenesis. We explored foradditional functions of MKS3p using RNA interference (...

    Authors: Tyler Picariello, Megan Smith Valentine, Junji Yano and Judith Van Houten

    Citation: Cilia 2014 3:2

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  6. Content type: Reviewer acknowledgement

    We would like to thank the following experts for their assistance with the peer-review in 2013 for manuscripts submitted to Cilia. We greatly appreciate the voluntary contribution made to the journal by all our r...

    Authors: Phil Beales and Peter K Jackson

    Citation: Cilia 2014 3:1

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  7. Content type: Research

    Lower airway abnormalities are common in patients with primary ciliary dyskinesia (PCD), a pediatric syndrome that results from structural or functional defects in motile cilia. Patients can suffer from recurr...

    Authors: Casey W McKenzie, Joshua M Klonoski, Taylor Maier, Glenda Trujillo, Peter F Vitiello, Victor C Huber and Lance Lee

    Citation: Cilia 2013 2:18

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  8. Content type: Research

    Most motile cilia and flagella have nine outer doublet and two central pair (CP) microtubules. Outer doublet microtubules are continuous with the triplet microtubules of the basal body, are templated by the ba...

    Authors: Karl-Ferdinand Lechtreck, Travis J Gould and George B Witman

    Citation: Cilia 2013 2:15

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  9. Content type: Research

    Circulation of cerebrospinal fluid (CSF) through the ventricular system is driven by motile cilia on ependymal cells of the brain. Disturbed ciliary motility induces the formation of hydrocephalus, a pathologi...

    Authors: Cathrin Hagenlocher, Peter Walentek, Christina Müller, Thomas Thumberger and Kerstin Feistel

    Citation: Cilia 2013 2:12

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  10. Content type: Research

    Cilia are found on nearly every cell type in the mammalian body, and have been historically classified as either motile or immotile. Motile cilia are important for fluid and cellular movement; however, the rol...

    Authors: Amber K O’Connor, Erik B Malarkey, Nicolas F Berbari, Mandy J Croyle, Courtney J Haycraft, P Darwin Bell, Peter Hohenstein, Robert A Kesterson and Bradley K Yoder

    Citation: Cilia 2013 2:8

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  11. Content type: Review

    The multinational SYSCILIA consortium aims to gain a mechanistic understanding of the cilium. We utilize multiple parallel high-throughput (HTP) initiatives to develop predictive models of relationships betwee...

    Authors: Teunis JP van Dam, Gabrielle Wheway, Gisela G Slaats, Martijn A Huynen and Rachel H Giles

    Citation: Cilia 2013 2:7

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  12. Content type: Research

    Ethanol has been shown to stimulate the beat frequency of respiratory cilia at concentrations encountered during social drinking, while one of its metabolites, acetaldehyde, has been shown to cause a marked de...

    Authors: Claire Mary Smith, Priya Radhakrishnan, Kulvinder Sikand and Chris O’Callaghan

    Citation: Cilia 2013 2:5

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  13. Content type: Reviewer acknowledgement

    We would like to thank all our reviewers for their contribution to the success of Cilia. Their voluntary participation has led to the launch of a new journal consistently publishing high quality articles and an i...

    Authors: Phil Beales and Peter K Jackson

    Citation: Cilia 2013 2:4

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  14. Content type: Review

    Pancreatic cysts are a heterogeneous group of lesions, which can be benign or malignant. Due to improved imaging techniques, physicians are more often confronted with pancreatic cysts. Little is known about th...

    Authors: Sophie J van Asselt, Elisabeth GE de Vries, Hendrik M van Dullemen, Adrienne H Brouwers, Annemiek ME Walenkamp, Rachel H Giles and Thera P Links

    Citation: Cilia 2013 2:3

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  15. Content type: Research

    Cilia are essential organelles in multiple organ systems, including the kidney where they serve as important regulators of renal homeostasis. Renal nephron cilia emanate from the apical membrane of epithelia, ...

    Authors: Sander G Basten, Sven Willekers, Joost SP Vermaat, Gisela GG Slaats, Emile E Voest, Paul J van Diest and Rachel H Giles

    Citation: Cilia 2013 2:2

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  16. Content type: Commentary

    Primary cilia have been previously linked to the central regulation of satiety. Thetubby mouse is characterized by maturity-onset obesity and blindness. Arecent paper demonstrates molecular defects in trafficking...

    Authors: Saikat Mukhopadhyay and Peter K Jackson

    Citation: Cilia 2013 2:1

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  17. Content type: Research

    The primary cilium is a microtubule-based, plasma membrane-ensheathed protrusion projecting from the basal bodies of almost all cell types in the mammalian body. In the past several years a plethora of papers ...

    Authors: Marc August Willaredt, Karin Gorgas, Humphrey A R Gardner and Kerry L Tucker

    Citation: Cilia 2012 1:23

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